isozyme in a sentence
Examples
- PKM2 is an isozyme of pyruvate kinase that is responsible for the Warburg effect in cancer cells.
- This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
- It is an inhibitor of cytochrome P450 CYP2D6 and may interfere with other drugs metabolized by this isozyme.
- For those diagnosed with essential pentosuria, the major isozyme appears to be the same as the minor one.
- This isozyme is ubiquitously expressed in adult human tissues, including liver, brain, kidney, and spleen.
- This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates.
- This may be compounded by the fact that dextromethorphan and chlorpheniramine are both metabolized by CYP2D6 isozyme of Cytochrome P450.
- Meanwhile, the muscle isozyme plays a major role in the cellular response to long-term adaptation to hypoxia.
- L-xylulose reductase, contained in red blood cells, is composed of both a major and minor isozyme.
- The human 17?-HSD1 isozyme is highly specific for estrogens over androgens whereas the rodent isozyme is less specific.