properdin meaning in Hindi

Examples

1. The C3bBb complex is stabilized by binding oligomers of factor P ( Properdin ).
2. C3b has different binding site for C3bINA, ?1H, factor B and properdin.
3. Properdin also inhibits the Factor H  mediated cleavage of C3b by Factor I.
4. The complex is believed to be unstable until it binds properdin, a serum protein.
5. Inherited properdin deficiency also is related, with an increased risk of contracting meningococcal disease.
6. As soon as binding occurs to the glomerulus, via interaction with properdin, complement is activated.
7. The properdin promotes the association of C3b with Factor B and provides a focal point for the assembly of C3bBb on a surface.
8. The addition of properdin forms the complex C3bBbP, a stable compound which can bind an additional C3b to form alternative pathway C5-convertase.
9. He led a team at Western Reserve University which discovered properdin in 1954, and this discovery received attention from the national press as a breakthorough in immunology.
10. Thrombospondin's activity has been mapped to several domains, in particular the amino-terminal heparin-binding domain, the procollagen domain, the properdin-like type I repeats, and the globular carboxy-terminal domain.