proguanil meaning in Hindi

Examples

1. Prophylaxis with mefloquine was compared to prophylaxis with atovaquone-proguanil.
2. Proguanil displays synergism when used in combination with the antimalarial atovaquone.
3. It is proposed that drugs such as proguanil act to disrupt retinoid homeostasis.
4. Atovaquone-proguanil is an effective alternative in patients unable to tolerate chloroquine.
5. This mechanism of action differs from when proguanil was used as a singular agent.
6. A standard tablet of Malarone contains 100 mg of proguanil hydrochloride and 250 mg of atovaquone.
7. A pediatric tablet contains 25 mg of proguanil hydrochloride and 62.5 mg of atovaquone.
8. Atovaquone / proguanil has been commercially available from GlaxoSmithKline since 2000, and its patent expired in 2013.
9. Proguanil, via its metabolite cycloguanil, functions as a dihydrofolate reductase inhibitor, halting parasitic deoxythymidilate synthesis.
10. The combination atovaquone-proguanil may be used in those patients who are unable to take chloroquine for whatever reason.