xenobiotic in a sentence
Examples
- Induction of enzymes involved in xenobiotic metabolism occurs through binding of the ligand-bound AhR to xenobiotic responsive elements in the promoters of genes for these enzymes.
- In subsequent phase II reactions, these activated xenobiotic metabolites are conjugated with charged species such as glutathione ( GSH ), sulfate, glycine, or glucuronic acid.
- Ethacrynic acid and its glutathione-adduct are potent inhibitors of glutathione " S "-transferase family members, which are enzymes involved in xenobiotic metabolism.
- XenoBiotic Laboratories, Inc ., USA, unpublished ) cited in There is a data gap on presence or formation of nitrosamines in apple metabolism or during processing.
- These monooxygenases are often misclassified because they share activity profiles similar to those of cytochrome P450 ( CYP450 ), which is the major contributor to oxidative xenobiotic metabolism.
- This non-xenobiotic role of yFMO may represent the original role of the FMO's before the rise of the modern FMO family of enzymes found in mammals.
- It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the catabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues.
- Among the low-weight pharmaceuticals, the xenobiotic and abiotic compounds, which have neither the natural analogs nor the structural similarity to the biological molecules, are of particular interest.
- In an attempt to make BPH control more species-specific, researchers are trying to develop methods of turning off specific BPH genes for digestion-, defense-and xenobiotic metabolism.
- Before they can be registered for sale in most countries, xenobiotic pesticides must undergo extensive evaluation for risk factors, such as toxicity to humans, ecotoxicity, or persistence in the environment.