alkylating agent in a sentence
Examples
- "' 2-Iodoacetamide "'is an alkylating agent used for peptide mapping purposes.
- Its toxicity correlates to its ability as an alkylating agent, which will modify cysteine residues in proteins.
- Inside cells, amifostine detoxifies reactive metabolites of platinum and alkylating agents, as well as scavenges free radicals.
- Diethyl sulfate is used as an alkylating agent to prepare ethyl derivatives of phenols, amines, and thiols.
- Allyl bromide is an alkylating agent used in synthesis of polymers, pharmaceuticals, allyls and other organic compounds.
- Methylation of the MGMT promoter in gliomas is a useful predictor of the responsiveness of tumors to alkylating agents.
- As an alkylating agent, it is useful in the manufacture of pharmaceuticals and pesticides, such as mustard oil.
- Cyclophosphamide and the related nitrogen mustard derived alkylating agent ifosfamide were developed by Norbert Brock and ASTA ( now FDA.
- It acts as an alkylating agent causing intra-strand and inter-strand cross-links between DNA bases.
- Secondary alkylating agents also react, but tertiary ones are usually too prone to side reactions to be of practical use.