thromboxane in a sentence

Examples

1. A heme group coordinated to a cysteine residue from the enzyme, thromboxane synthase, is involved in the mechanism.
2. "' Ozagrel "'( INN ) is an antiplatelet agent working as a thromboxane A2 synthesis inhibitor.
3. Unlike thromboxane synthase inhibitors such as ozagrel, seratrodast does not affect thrombus formation, time to occlusion and bleeding time.
4. These " Sticky platelets " secrete several chemicals, including thromboxane A2 that stimulate vasoconstriction, reducing blood flow at the site.
5. The human thromboxane A ( TXA ) synthase is a 60 kDa protein with 533 amino acids and a heme prosthetic group.
6. It also sometimes is used to reduce platelet aggregation by inhibiting degranulation of platelets which reduces the release of ADP and thromboxane.
7. Aspirin blocks an enzyme, cyclo-oxygenase, that is involved in producing thromboxane, a substance that induces platelets to clump.
8. Aspirin works by blocking the formation of thromboxane A2, a chemical in the body that makes platelets sticky and promotes blood clotting.
9. However the serotonin and the thromboxane A2 cause more contraction of the smooth muscle cells and as a result contractions outweigh the relaxations.
10. In catalyzing the synthesis of thromboxanes, TXA synthase is involved in a flux pathway that can modulate the amount of thromboxane produced.