schiff base in a sentence
Examples
- The PLP is anchored by means of a lysine, which forms an aldimine Schiff base linkage with the PLP aldehyde.
- For example, Schiff base formation can be categorized as a forming new covalent bonds between a carbonyl and primary amine.
- Retinal binds covalently to a lysine on the transmembrane helix nearest the C-terminus of the protein through a Schiff base linkage.
- If this group is " not " a hydrogen atom, then the compound can sometimes be referred to as a Schiff base.
- The second water molecule is a product of the dehydration of the carbinolamine that leads to the formation of the Schiff base.
- The Mannich reaction is an example of nucleophilic addition of an amine to a carbonyl group followed by dehydration to the Schiff base.
- The reaction mechanism proceeds via the formation of a Schiff base intermediate, which is covalently attached to lysine 115 in the active site.
- The Lysine, which is involved in the formation of the Schiff base is coordinated by a phosphate ion and two solvent water molecules.
- The term Schiff base is normally applied to these compounds when they are being used as ligands to form coordination complexes with metal ions.
- These results provided support that the mechanism proceeds through a Schiff base intermediate between the ketoacid and an amino acid residue on the enzyme.