glucuronic acid in a sentence
Examples
- Glucuronic acid is attached via a glycosidic bond to the substance, and the resulting glucuronide, which has a much higher water solubility than the original substance, is eventually excreted by the kidneys.
- The O-linked glycan chains predominantly contain galactose, arabinose, rhamnose, mannose, galacturonic acid and / or glucuronic acids and have a relatively high degree of polymerization, with a structure similar to arabinogalactan II.
- It is a precursor of glycogen and can be converted into UDP-galactose and UDP-glucuronic acid, which can then be used as substrates by the enzymes that make polysaccharides containing galactose and glucuronic acid.
- There is no internationally accepted molecular standard for the composition of heparin, as it is a complex polymer of GAG units and uronic acids ( including D-glucuronic acid, L-iduronic acid, and D-glucosamine ).
- It is a precursor of glycogen and can be converted into UDP-galactose and UDP-glucuronic acid, which can then be used as substrates by the enzymes that make polysaccharides containing galactose and glucuronic acid.
- Moreover, glucuronolactone is hydrolyzed in the body ( like butyrolactone ) to glucuronic acid, which may be oxidized to glucaric acid, or isomerized to another hexuronic acid, so there is no reasonable toxicity mechanism.
- The reaction catalyzed by the UGT enzyme involves the addition of a glucuronic acid moiety to xenobiotics and is the most important pathway for the human body's elimination of the most frequently prescribed drugs.
- With his pupil Hans Horst Meyer he discovered glucuronic acid as a conjugation partner in xenobiotic metabolism and later found that glucuronic acid was also a component of cartilage and occurred as a disaccharide of chondroitin sulfate.
- With his pupil Hans Horst Meyer he discovered glucuronic acid as a conjugation partner in xenobiotic metabolism and later found that glucuronic acid was also a component of cartilage and occurred as a disaccharide of chondroitin sulfate.
- The innate utilization of sugars as solubilizing moieties in Phase II and III metabolism ( glucuronic acids ) has remarkably allowed an evolutionary advantage in that mammalian enzymes are not directly evolved to degrade O glycosylated products on larger moieties.