nicotinic acid in a sentence
Examples
- In alternate terminology, it is known as " nicotinic acid diethylamide ", which meaningfully emphasizes its laboratory origins, and of which its common name is derived as a blend.
- Flushing occurs in many patients treated therapeutically with nicotinic acid, and as a result, nicotinamide holds more clinical value as it is not associated with the same uncomfortable flushing.
- For example, the enzyme nicotinamidase, which converts nicotinamide to nicotinic acid, is a target for drug design, as this enzyme is absent in humans but present in yeast and bacteria.
- This form of niacin is supposed to reduce or prevent flushing by being broken down into the metabolites Niacin ( aka Nicotinic acid ) and Inositol at a slower rate.
- High dose nicotinic acid is used as an agent that elevates high-density lipoprotein cholesterol, lowers low-density lipoprotein cholesterol and lower free fatty acids through a mechanism that is not completely understood.
- The product of this reaction, phosphoribosyl pyrophosphate ( PRPP ), is used in numerous biosynthesis ( NAD : the reaction of PRPP with nicotinic acid yields the intermediate nicotinic acid mononucleotide.
- Conrad Elvehjem isolated nicotinic acid ( niacin ) at the Agricultural Chemistry Building in 1937, which cured pellagra . and Karl Paul Link identified the blood coagulant dicumarol here in 1941.
- The product of this reaction, phosphoribosyl pyrophosphate ( PRPP ), is used in numerous biosynthesis ( NAD : the reaction of PRPP with nicotinic acid yields the intermediate nicotinic acid mononucleotide.
- Cholesterol is the main constituent of atheroma, the fatty lumps in the wall of dietary measures, such as a low-fat diet, and poorly tolerated medicines, such as clofibrate, cholestyramine, and nicotinic acid.
- Leete at al further refined this model in 1989, and showed that it was trigonelline ( nicotinic acid methylated at the nitrogen ) that served as an intermediate in the biosynthesis of dioscorine.