microsome in a sentence
Examples
- In human liver microsomes, cytochrome P450-mediated styrene oxidation showed the production of more " S " enantiomer relative to the " R " enantiomer.
- The "'microsomal ethanol oxidizing system "'( MEOS ) is an alternate pathway of ethanol metabolism that occurs in the microsome in the oxidation of ethanol to acetaldehyde.
- The loss of cytochrome P-450 and monooxygenase activity seen on incubation of liver microsomes with ANTU is likely the result of the covalent binding of atomic sulfur to cytochrome P-450.
- Some lots are available to study specific populations ( example : lung microsomes from smokers or non-smokers ) or divided into classifications to meet target CYP activity levels for inhibition and metabolism studies.
- Within the cell, GGT is located in microsomes and along the biliary tract plasma membrane, GGT is more commonly measured than 5-NT because GGT testing is widely available on a variety of laboratory instruments.
- In contrast to these finding from rat liver microsomes, mammalian acyl transferase from dog lungs was found to exhibit no preference between 1-lyso-2-acyl-phosphatidylcholine and 1-acyl-2-lyso-phosphatidylcholine.
- A subset of Cytochrome P450 ( CYP450 ) microsome-bound ?-hydroxylases ( see 20-Hydroxyeicosatetraenoic acid ) metabolize arachidonic acid to 20-Hydroxyeicosatetraenoic acid ( 20-HETE ) and 19-hydroxyeicosatetraenoic acid by an omega oxidation reaction.
- It is metabolized in human hepatocytes and human microsomes to form [ 2-( 2', 6'- dichloro-4'- hydroxy-phenylamino ) phenyl ] acetoxyacetic acid as the major metabolite, which is then further conjugated.
- The C-hydroxylated metabolites may be considered as the detoxication products, while the benzenediazonium ion ( BDI ) formed by microsome-catalyzed enzymatic splitting of the azo group of Sudan I, reacts with DNA " in vitro > ".
- The expression of CYP1A1 in human livers is low, less than 0, 7 % of the total hepatic CYP expression, while it contributes up to 12 to 30 % in the oxidation of Sudan I in a set of human liver microsomes.