grignard reagent in a sentence

Examples

1. Grignard reagents and organolithiums will act as bases rather than nucleophiles, and will simply deprotonate the amide.
2. These compounds react readily with nucleophiles like water, alcohols, amines, thiols, and Grignard reagents.
3. The ester groups are susceptible to reaction with aryl Grignard reagents, leading after hydrolysis to the diol.
4. The simple oxidation of Grignard reagents to give alcohols is of little practical import as yields are generally poor.
5. Reaction of a Grignard reagent with triethyl orthoformate gives an acetal, which can be hydrolyzed to an aldehyde.
6. The silver mesitylene adduct is a tetramer . it can be formed from silver chloride and the Grignard reagent:
7. Grignard reagents can also reduce a boronic ester [ RB ( OR') 2 ] to a borinic ester.
8. In such cases the organozinc compound is usually prepared by transmetallation from an organolithium or a Grignard reagent, for example:
9. As with acid halides and anhyrides, they will react with an excess of a Grignard reagent to give tertiary alcohols.
10. It was first prepared by the reaction of chlorodiphenylphosphine with the Grignard reagent derived from the protected bromobenzaldehyde followed by deprotection.