periodic paralysis in a sentence

Examples

1. A landmark 1990 study of a large family with a tendency toward hyperkalemic ( high-potassium ) periodic paralysis helped identify the mutation responsible.
2. The channelopathies of human skeletal muscle include hyper-and hypokalemic ( high and low potassium blood concentrations ) periodic paralysis, myotonia congenita and paramyotonia congenita.
3. In 1935 Mary Walker was the first to recognise the association between the condition familial periodic paralysis and hypokalaemia ( low blood potassium levels ).
4. In hyperkalemic periodic paralysis, mutations occur in residues between transmembrane domains III and IV which make up the fast inactivation gate of Na v 1.4.
5. In contrast, hyperkalemic periodic paralysis refers to gain-of-function mutations in sodium channels that maintain muscle depolarisation and therefore are aggravated by high potassium ion concentrations.
6. Although agitation is often assumed to be a positive sign of conversion disorder, release of epinephrine is a well-demonstrated cause of paralysis from hypokalemic periodic paralysis.
7. The association with the R83H mutation in KCNE3 is controversial and other groups have detected the same mutation in individuals not exhibiting symptoms of periodic paralysis.
8. Patients with the rare hereditary condition of hyperkalemic periodic paralysis appear to have a heightened muscular sensitivity that is associated with transient elevation of potassium levels.
9. These changes disrupt the flow of potassium ions in skeletal and cardiac muscle, leading to the periodic paralysis and irregular heart rhythm characteristic of Andersen Tawil syndrome.
10. Acetazolamide ( " Acet " ) is used for treating horses with the genetic disease hyperkalemic periodic paralysis ( HYPP ), and prevents affected animals from having seizures.