nephrotoxic in a sentence
Examples
- Bernt Krebs was able to develop a number of highly interesting new compounds with promising properties, e . g ., without nephrotoxic side effects.
- Polymixin B prevents endotoxin from binding to inflammatory cells, but is potentially nephrotoxic, so should be used with caution in horses with azotemia, especially neonatal foals.
- However, this is not always an option; in such a situation, alternative drug therapy may be employed, if possible, to avoid this deleterious nephrotoxic.
- The obsolete ( as an anaesthetic ) agent methoxyflurane had a nephrotoxic effect and caused acute renal failure, usually attributed to the liberation of fluoride ions from its metabolism.
- Patients with kidney loss should be monitored for hypertension ( and treated for it if discovered ) and avoid nephrotoxic drugs such as certain pain relievers and IV contrast agents.
- Imipenem is hydrolyzed in the mammalian kidney by a dehydropeptidase enzyme to a nephrotoxic intermediate, and thus is co-formulated with the dehydropeptidase inhibitor cilastatin . and intramuscular formulations.
- Among the accidental causes of renal failure is the crush syndrome, when large amounts of toxins are suddenly released in the blood circulation after a long compressed nephrotoxic metabolites of myoglobin.
- "' Aristolochic acids "'( ) are a family of carcinogenic, mutagenic, and nephrotoxic compounds commonly found in the birthwort ( Aristolochiaceae ) family of plants.
- In short, it is nephrotoxic, neurotoxic, increases the risk of squamous cell carcinoma and infections, and often causes hypertension ( due to renal vasoconstriction and increased sodium reabsorption ).
- Both species caused renal damage only, the changes of which corresponded to tubulo-interstitial nephritis . " C . gentilis " has been found to be nephrotoxic to rats.