demethylation in a sentence
Examples
- Sulpiride, along with clozapine, has been found to activate DNA demethylation in the brain.
- Current antipsychotic drugs, like clozapine and sulpiride, have been shown to also induce demethylation.
- Maeder et al . has constructed a ZF-TET1 protein for use in DNA demethylation.
- After N-demethylation of oxymorphone, noroxymorphone is further glucuronidated to noroxymorphone-3-glucuronide.
- Histones H3 and H4 can also be manipulated through demethylation using histone lysine demethylase ( KDM ).
- The demethylation occurs when JmjC utilizes multiple cofactors to hydroxylate the methyl group, thereby removing it.
- Further processing of aristolactam I by O-demethylation results in aristolactam Ia, the primary metabolite.
- Codeine is metabolised by O-and N-demethylation in the liver to morphine and norcodeine.
- The demethylation of sarcosine catalyzed by sarcosine dehydrogenase can proceed with or without the presence of tetrahydrofolate.
- They prevent the demethylation of the H3K4 histone protein and open up that part of the chromatin.