mannich reaction in a sentence
Examples
- This process occurs through an oxidation, which regenerates the pyrrolinium cation and formation of an enolate anion, and an intramolecular Mannich reaction.
- The compound is formed by reaction of ethylene urea with a 37 % solution of formalin and hydrochloric acid in a sequence of Mannich reactions.
- Biosynthesis of monoterpenoid indole alkaloids begins with the Mannich reaction of tryptamine and secologanin; it yields strictosidine which is converted to 4, 21-dehydrogeissoschizine.
- Imines synthesized in this fashion have been shown to undergo a one-pot Mannich reaction with 1, 3-dicarbonyl compounds, such as protected imine.
- To obtain the primary thia-?-Ala-OMe intermediate, a sequence of condensation, Mannich reaction, and palladium-catalyzed decarboxylation steps were performed.
- Chloroiodomethane is used in cyclopropanation ( " Simmon-Smith reaction " ), Mannich reaction, aminomethylation, epoxidation, ring opening and addition to terminal alkenes.
- The two reactants ( imine and enamine ) line up for the Mannich reaction with Si facial attack of the imine by the Si-face of the enamine-aldehyde.
- A reverse Pictet-Spengler reaction cleaves the C2 C3 bond, while a subsequent Mannich reaction forms the C3 C7 bond, and a Michael addition forms the C2 C16 bond to provide dehydropreakuammicine.
- The aza-Cope / Mannich reaction shows high diastereoselectivity, generally in accordance the results of allyl and amine substituents are installed on a ring, and thus cis or trans to one another.
- "' Acrylophenone "'is an organic compound with the formula C 9 H 8 O . It is prepared using acetophenone, formaldehyde, and an amine hydrochloride in a Mannich reaction.