hydrazone in a sentence

Examples

1. When R 3 is OH, the imine is called an oxime, and when R 3 is NH 2 the imine is called a hydrazone.
2. The reactants are an aryl diazonium salt obtained from reaction of the corresponding aniline with sodium nitrite and hydrochloric acid and the hydrazone of pyruvic acid.
3. The chelation of lithium cation with the methoxy group is one of the most important features of the transition state for Enders'hydrazone alkylation reaction.
4. Another early application is the synthesis of unnatural chiral amino acids in a formal reductive amination for example starting from benzophenone and the hydrazone of benzoyl chloride:
5. The hydrazone-based bond is stable at neutral pH ( in the blood ), but is rapidly destroyed in the acidic environment of lysosomes of the cell.
6. The payload is the chemotherapy drug doxorubicin which is connected with a hydrazone linker to cysteine residues of the Lewis-Y specific ( chimeric ) monoclonal antibody BR96.
7. "' Amdro "'is a trade name for a hydramethylnon-based hydrazone insecticide, commonly used in the southern United States for fire ant control.
8. In the original Barton publication the reaction was optimized by using a strong guanidine base, the inverse addition of the hydrazone to an iodine solution, and by exclusion of water.
9. Hydrazone-based coupling methods are used in medical biotechnology to couple drugs to targeted antibodies ( see ADC ), e . g . antibodies against a certain type of cancer cell.
10. However, their subsequent investigations identified that both the disulfide and hydrazone covalent bonds exhibit effective component exchange processes and so present a reliable means of generating dynamic combinatorial libraries capable of thermodynamic templation.