frequency of mutation in a sentence

Examples

1. If genetic disorders are defined by the existence of deleterious alleles, then natural selection acting over evolutionary time would result in a lower frequency of mutations than are currently observed.
2. Tuna and Amos have summarized the mutation frequencies per megabase ( Mb ) in some carcinomas, as shown in the table ( along with the indicated frequencies of mutations per genome ).
3. When expression of DNA repair genes is reduced, DNA damages accumulate in cells at a higher than normal level, and these excess damages cause increased frequencies of mutation and / or epimutation.
4. In outbred populations, the relative frequency of mutations in the four genes is alpha > > beta > > gamma > > delta in an 8 : 4 : 2 : 1 ratio.
5. Cellular response to mannan in ASCA + peripheral blood lymphocytes could be inhibited by adding MBL, however, a high frequency of mutations in the MBL gene was found in ASCA + patients.
6. In the more scaled-down 384-well plate microfluctuation method the frequency of mutation is counted as the number of wells out of 48 which have changed color after 2 days of incubation.
7. In genetics, a "'mutagen "'is a physical or chemical agent that changes the genetic material, usually DNA, of an organism and thus increases the frequency of mutations above the natural background level.
8. A high frequency of mutation of the G551D gene CFTR ( cystic fibrosis transmembrane conductance regulator ), causing cystic fibrosis is found in the Czech Republic, Austria, and among the Celtic nations : Wales, Scotland, Cornwall, Ireland and Brittany.
9. The high frequencies of mutations in the total nucleotide sequences within cancers suggest that often an early alteration in the field defects giving rise to a cancer ( e . g . yellow area in the diagram in this section ) is a deficiency in DNA repair.
10. With a DNA repair deficiency, more DNA damages remain in cells at a higher than usual level ( 5th level from the top in figure ), and these excess damages cause increased frequencies of mutation and / or epimutation ( 6th level from top of figure ).