enterohepatic circulation in a sentence
Examples
- That long-lasting action was most likely due to slow dissociation of the enzyme-inhibitor complex and an active oxide metabolite that undergoes enterohepatic circulation.
- He published fundamental work on the enterohepatic circulation of bile acids and how disturbances in ileal function such as those found in Crohn's disease can produce chronic diarrhea.
- All four of these bile acids can be taken back up into the blood stream, return to the liver, and be re-secreted in a process known as enterohepatic circulation.
- Owing to the extremely efficient enterohepatic circulation of B 12, the liver can store 3 to 5 years worth of vitamin B 12; therefore, nutritional deficiency of this vitamin is rare.
- A trace ( ~ 1 % ) of the urobilinogen is reabsorbed into the enterohepatic circulation to be re-excreted in the bile : some of this is instead processed by the kidneys, coloring the urine yellow.
- Aramchol was initially intended to combine a cholesterol solubilising moiety ( a saturated fatty acid ) with a bile acid ( cholic acid ) acting as a vehicle to enable secretion into bile and entry into the enterohepatic circulation to solubilise bile stones.
- Benoxaprofen has a rather long half life in man ( t 1 / 2 = 20-30 h ), undergoes biliary excretion and enterohepatic circulation and is also known to have a slow plasma clearance ( CL p = 4.5 ml / min ).
- In September 1994, Jefferson first articulated the Hologenome Theory of Evolution, at a presentation at Cold Spring Harbor Laboratory, at a Symposium " A Decade of PCR " This theory was developed from his molecular and genetic work on glucuronide metabolism by vertebrate-associated microbes, including the role of glucuronidases, sulfatases and other enzymes in modulating and effecting enterohepatic circulation of steroid hormones.