degranulation in a sentence
Examples
- Other membrane activation events can either prime mast cells for subsequent degranulation or act in synergy with Fc?RI signal transduction.
- It is a lysosomal protein stored in azurophilic granules of the neutrophil and released into the extracellular space during degranulation.
- Neurotensin is involved in many processes including mast cell degranulation and regulation of central nervous system dopaminergic and cholinergic circuits.
- Antibodies will also trigger vasoactive amine degranulation to contribute to immunity against certain types of antigens ( helminths, allergens ).
- They block a calcium channel essential for mast cell degranulation, stabilizing the cell, thus preventing the release of histamine.
- If the degranulation is widespread, it can cause a shock-like syndrome similar to that of an allergic reaction.
- The degranulation of mast cells is very easily triggered, as was evidenced by the controversial Nature paper by Jacques Benveniste.
- Interleukin-8 is a key mediator associated with inflammation where it plays a key role in neutrophil recruitment and neutrophil degranulation.
- Crosslinking of the Fc?RI via IgE-antigen complexes leads to degranulation of mast cells or basophils and release of inflammatory mediators.
- Under laboratory conditions, degranulation of isolated basophils can also be induced with antibodies to the Fc?RI?, which crosslink the receptor.