• आदिचर्मपेशी खंड |
dermomyotome meaning in Hindi
dermomyotome sentence in HindiExamples
More: Next- In the absence of Tbx6, the central dermomyotome of zebrafish fails to develop.
- Myf5 is expressed in the dermomyotome of the early somites, pushing the myogenic precursors to undergo determination and differentiate into myoblasts.
- Tbx6 is also required for the segmentation of the paraxial mesoderm into somites, and for the normal development of the dermomyotome in zebrafish.
- During embryogenesis, the dermomyotome and / or myotome in the somites contain the myogenic progenitor cells that will evolve into the prospective skeletal muscle.
- Termed the early epaxial enhancer, its activation provides the " go " signal for expression of Myf5 in the epaxial dermomyotome, where it is first seen.
- Because the sclerotome differentiates before the dermatome and the myotome, the term " dermomyotome " refers to the combined dermatome and myotome before they separate out.
- The determination of dermomyotome and myotome is regulated by a gene regulatory network that includes a member of the T-box family, tbx6, ripply1, and mesp-ba.
- Specifically, it is first seen in the dorsomedial portion of the dermomyotome, which develops into the epaxial myotome . it is instead directly activated by the transcription factor Pax3 in hypaxial cells.
- PAX3 is generally expressed at its highest levels during embryonic development and is expressed at a lesser degree during the fetal stages; it is expressed in migrating hypaxial cells and dermomyotome cells, but is not expressed at all during the development of facial muscle.