axotomy meaning in Hindi

Examples

1. Axotomy also induces the loss of basophilic staining in the event of central chromatolysis of the neuronal cell.
2. Expression is also increased after axonal injury, such as peripheral axotomy in motor neurons and dorsal root ganglia.
3. Using the experimental model provided by the facial motor nucleus following axotomy Kreutzberg and his fellow workers discovered essential parameters of the regeneration program of nerve cells.
4. One hypothesis behind the incidence of chromatolysis following axotomy is that the shortening of the axon prevents the incorporation of the axonal cytoskeleton that undergoes formation in the injured neuron.
5. In mature animals, where survival factors are derived locally or via autocrine loops, axotomy of peripheral neurons and motoneurons can lead to a robust regenerative response without any neuronal death.
6. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy.
7. Axotomy may cause neuronal cell death, especially in embryonic or neonatal animals, as this is the period in which neurons are dependent on their targets for the supply of survival factors.
8. In experiments where deafferentation or axotomy was performed in the lateral geniculate nucleus ( LGN ) of cats it was found that pre-synaptic dendrites began to form to compensate for the lost axons.
9. This type of dendritic reactive synaptogenesis is thought to occur in order to re-saturate the region which has become vacant postsynaptic sites following neurodegeneration caused by deafferentation or axotomy in order to restore partial functionality to the affected region.
10. Galanin is linked to a number of diseases including Alzheimer's disease, epilepsy as well as neuroprotective activity as its biosynthesis is increased 2-10 fold upon axotomy in the peripheral nervous system as well as when seizure activity occurs in the brain.