antiglobulin meaning in Hindi

Examples

1. Rheumatoid factor, cryoglobulins, direct antiglobulin test and cold agglutinin titre results can be positive.
2. A direct antiglobulin test ( Coombs test ) is also performed as part of the antibody investigation.
3. To determine the autoantibody or autoantibodies present in a patient, the Coombs test, also known as the antiglobulin test, is performed.
4. There are two types of Coombs tests, direct and indirect; more commonly, the direct antiglobulin test ( DAT ) is used.
5. It can also be ordered along with a direct antiglobulin test when a patient is suspected of having a transfusion reaction or symptoms of autoimmune hemolytic anemia.
6. Antigen negative units are then tested against the patient plasma using an antiglobulin / indirect crossmatch technique at 37 degrees Celsius to enhance reactivity and make the test easier to read.
7. Diagnosis of autoagglutination can be confirmed by a positive  Direct Antiglobulin Test aka Direct Coomb s test using Coomb s serum ( positivity is seen in 75 % of cases)
8. In 1946, Boorman, Dodd, and Loutit applied the direct antiglobulin test to a variety of hemolytic anemias, and laid the foundation for the clear distinction of autoimmune from congenital hemolytic anemia.
9. Laboratory assessment is based on a positive Direct Antiglobulin Test ( DAT ), a decrease in serum haptoglobin, and an increase in blood levels of the enzyme lactate dehydrogenase and indirect bilirubin levels.
10. Of these developments, the antiglobulin test described by Coombs, Mourant, and Race in 1945 has proved to be one of the more important, useful tools now available for the detection of immune hemolytic states.